Manchester United have endured a disastrous start to their season, losing 2-1 to Brighton and Hove Albion in their opening game before losing 4-0 to Brentford last time out.
The Reds have also struggled to impress in the Premier League this season, playing out consecutive 1-1 draws against Fulham and Crystal Palace in their first and second games respectively.
Liverpool ran riot in this fixture last season and Erik ten Hag is now tasked with avoiding a repeat of such.
When and where will the game take place?
The Red Devils will return to Old Trafford for this one after a horror showing in their game on the road last weekend.
The blockbuster clash will be played on Monday the 22nd as the final game of matchday three. The game will be live on Sky Sports, and those unable to catch Sky can also stream Man Utd games live.
The Old Trafford outfit have begun the season in abysmal fashion and find themselves rock-bottom in the league table.
In a scamper for reinforcements in the final days of the transfer window, United have landed Real Madrid midfielder Casemiro in a €70 million deal.
The move remains subject to medicals and a work permit but the Brazilian could be in the stands on Monday.
While Victor Lindelof remains out with an injury, Anthony Martial has returned from his spell on the sidelines although it is yet to be seen if the Frenchman is fit enough to start.
Jurgen Klopp’s men, who sit 12th in the Premier League standings, have conceded the first goal in both of their league outings this season and will be looking to avoid that next week.
The German manager, who previously said the club would not make more signings for the sake of it, may be forced to reconsider with their injury list piling up very early in the season.
Joel Matip, Thiago Alcantara, Ibrahima Konate, Curtis Jones, Diogo Jota, Alex Oxlade-Chamberlain, Calvin Ramsay and Caoimhin Kelleher have all been ruled out with injuries and will not play on Monday although Robert Firmino and Naby Keita are set to feature.
Summer signing Darwin Nunez received a red card against the Eagles last time out and has been suspended from this one.
Players to Watch – Malacia vs Salah
Monday’s game is another edition of one of the biggest rivalries in English football and with both sides seeking their first league win of the season, the managers are expected to field their strongest possible XI from the jump.
Tyrell Malacia has come off the bench in United’s two outings this season when the games were more or less lost and could be handed his first start of the season on Monday after a commendable second-half performance against Brentford.
Salah, meanwhile, scored five goals in this matchup last season and will become the all-time top scorer in the history of the rivalry should he score on Monday.
United’s new left-back is now set for one of his toughest tests yet in professional football and it will be interesting to see how he fares.
Manchester United’s Best Line Up Against Liverpool
Manchester United (4-3-3): David De Gea; Diogo Dalot, Harry Maguire, Lisandro Martínez, Tyrell Malacia; Fred, Christian Eriksen, Bruno Fernandes; Jadon Sancho, Marcus Rashford, Cristiano Ronaldo